"Inference of Gene Relations from Microarray Data by Abduction"
Irene Papatheodorou
 
Abstract: 
We describe an application of Abductive Logic Programming (ALP) to the 
analysis of an important class of DNA microarray experiments. We develop 
an ALP theory that provides a simple and general model of how gene 
interactions can cause changes in observable expression levels of genes. 
Input to the procedure are the observed microarray results; output are 
hypotheses about possible gene interactions that explain the observed 
effects. We apply and evaluate our approach on microarray experiments on 
M.tuberculosis and S.cerevisiae.

 
Irene Papatheodorou is a PhD student at the Department of Computing, 
Imperial College London since October 2002. Research objectives: applying 
AI methods to the analysis of biological data. Previous academic achievements
include an MSc in Computational Genomics and Bioinformatics at Imperial 
College (2001-2002) and a B.Sc in Human Genetics at University College 
London (1998-2001).